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Imagerie cérébrale Karalis

Neuronal Circuits & Brain Dynamics

Portrait Nikolas Karalis
Nikolas KARALIS

PhD, Team Leader, PI, INSERM

Team presentation

The "Neuronal Circuits & Brain Dynamics" team is interested in the organization of neural circuits and how the collective action of neurons gives rise to complex and emerging brain dynamics and behaviour.

The team is focusing on how neurochemicals and body signals influence the brain:

  • She is studying how the simultaneous release of neuromodulators, such as dopamine and serotonin, influences the activity of neurons and the coordination of brain regions.
  • She also studies how body signals, such as respiration, serve as fundamental elements of the architecture of the oscillatory circuit.
  • She uses her approach to study brain dynamics during behaviour and sleep and their involvement in transforming fleeting experiences into long-term memories.

To answer these fundamental questions about the nature and function of the brain, the team is combining a series of advanced neurotechnologies that allow us to observe and control brain activity:

  • It uses electricity and light to "read" and "write" information and memories in the brain
  • She uses genetics to modify the activity and architecture of neural circuits.
  • She uses mathematics to analyze and model our data and to better understand brain activity.

Using these approaches, we aim to identify and explore the fundamental principles of neural circuit organization and apply our understanding to the betterment of the human condition.

Team members

Portrait Nikolas Karalis
Nikolas KARALIS

PhD, Team Leader, PI, INSERM

News from the team

erc
Nikolas Karalis, team leader at the Paris Brain Institute, is awarded the ERC Starting Grant 2024.
The European Research Council's (ERC) Starting Grants are prestigious and highly competitive awards, designed to enable young scientists to build their research team, and to carry out ambitious and innovative projects addressing unexplored scientific ...
09.16.2024 Institutional
Portrait Nikolas Karalis
Nikolas Karalis : exploring the brain dynamics of our internal states
Nikolas Karalis joined the Brain Institute in January 2024. His work will focus on the fundamental link between brain activity and neurotransmitter balance. ...
02.15.2024 Portraits
bienvenue
Welcome aboard!
As part of the call for the group leader position launched in spring 2021, two young researchers have been selected from 260 to develop their own research teams within the Institute. These two teams will develop completely new scientific and ...
07.20.2023 Institutional