HUILLARD Emmanuelle
PhD, Team Leader, PI
PEYRE Matthieu
Clinician, MD,PhD,MCU-PH, Team Leader, PI, Sorbonne Université, AP-HP
Team presentation
Understanding the structure and function of neurovascular interfaces in health and disease, in the context of vascular malformations and brain tumors.
The four main objectives are:
- Improving diagnosis and treatment by developing a molecular database
- Characterize the function of new mutations identified in gliomas using an analytical "pipeline" developed by the team
- Identify the intrinsic and microenvironment-related cellular mechanisms responsible for tumour development and progression
- Develop new mouse and human models for validating new treatments
Main publications
- Peyre M, et al. Progestin-associated shift of meningioma mutational landscape. Ann Oncol 2018 Mar 1;29(3):681-686.
Team members
HUILLARD Emmanuelle
PhD, Team Leader, PI
PEYRE Matthieu
Clinician, MD,PhD,MCU-PH, Team Leader, PI, Sorbonne Université, AP-HP
KALAMARIDES Michel
Project Sponsor, MD, PhD, PU-PH, PI, Sorbonne Université, AP-HP
LENCK Stéphanie
Interventional Neuroradiologist, PhD student, PI
THOMAS Jean-Leon
Project Sponsor, PhD, DR1, PI, INSERM