Skip to main content

Or 34,00 After 66% tax deduction

I make a monthly donation I make an IFI donation
Organoïde cortical en microscopie confocale

Cellular and molecular neurobiology

Research Area

Last update: 28/05/2025 Reading time: 1min

The main objective of the teams in this area is to identify the genetic, molecular and cellular mechanisms that underlie brain function during development and aging.

This fundamental knowledge is essential for understanding major brain functions and neurological and psychiatric diseases in order to develop new therapeutic targets.

Mobilization of teams

Mobilization of teams

Paris Brain Institute teams in molecular and cellular neuroscience are engaged in a collaborative effort to understand normal brain and spinal cord development and the causes of their dysfunction in aging and neurological diseases (neurodegenerative diseases, multiple sclerosis, epilepsy, brain tumours, etc.).

Paris Brain Institute strategy is to assess the influence of genetics, dissect the molecular machinery of intracellular signaling, elucidate the role of different cell types, and understand complex cellular interactions in the normal or pathological state. The elucidation of the molecular and cellular bases of disorders of the nervous system allows us to understand the mechanisms of diseases and to develop new approaches to diagnose and treat them.

News that might interest you

Le développement du cerveau a une part d’aléatoire
The stochastic aspect of brain development
Although every person’s personality is the result of genetic and environmental factors, these are not the only factors at play. Bassem Hassan and his team at Paris Brain Institute have discovered that, in fruit flies (drosophila), individuality also...
05.12.2025 Research, science & health
Analyse MERSCOPE
New treatment pathways for brain malformation-linked focal epilepsy?
A study by Stéphanie Baulac’s team has revealed somatic mutations in different cell types in patients with type 2 focal cortical dysplasia. This disease causes drug-resistant epileptic seizures, for which the main treatment option is currently...
05.12.2025 Research, science & health
Un iceberg
The ICEBERG cohort, 10 years of collective scientific and medical mobilization
The ICEBERG cohort, initiated 10 years ago, is interested in studying factors predictive of the onset and progression of Parkinson’s disease.
05.15.2025 Research, science & health
La huntingtine est une protéine indispensable au développement embryonnaire, à la formation et au maintien du tissu cérébral.
Huntington's Disease: The Energy Hypothesis Gets Traction
Huntington's disease, a rare hereditary neurological disorder, is associated with an energy deficit that precedes the onset of symptoms and is closely linked to their progression. At Paris Brain Institute, Fanny Mochel and her colleagues are testing...
02.11.2025 Research, science & health
À la recherche de marqueurs d’imagerie dans la démence frontotemporale
Searching for Imaging Markers in Frontotemporal Dementia
Could exploring the relationships between different brain networks help us understand frontotemporal dementia (FTD)? This neurodegenerative disease, which progresses at varying rates, is often diagnosed late—when clinical signs are already severe. At...
01.07.2025 Research, science & health
Monocyte – un globule blanc qui se différencie en macrophage. Crédit : Université d’Edinbourg.
Discovery of a Macrophage Anomaly in Multiple Sclerosis
Certain patients with multiple sclerosis (MS) can partially regenerate myelin—the protective sheath that surrounds nerve fibers—which is damaged during the evolution of the disease. In studying how immune cells influence this remyelination...
12.19.2024 Research, science & health
See all our news