From 24 to 26 October 2025, Paris Brain Institute hosted the fifth edition of Interglitches, the charity speedrun marathon organised by the association Le French Restream.
Since its inception, this event has brought together a loyal community around a common goal: to support neuroscience research by showcasing the passion of video gaming, performance and cohesion. Once again this year, the event confirmed its singularity: three days of live marathon, an auditorium transformed into a real game scene and hundreds of spectators mobilized on Twitch and on the spot.
Once again this year, the sixty speedrunners and speedrunners present offered demonstrations of excellence and technical precision on many retro and current video games. Over the course of the challenges, they have shared their passion and sometimes their doubts with a public that closely follows every record attempt.
The speedrun consists of finishing a video game as quickly as possible, exploiting perfect control of the gameplay and sometimes tricks or glitches authorized by the community.
As every year, the Edmond and Lily Safra auditorium has been set up to welcome both players, the public present on site and the scientists of Paris Brain Institute invited to intervene. The hybrid format, both theatrical and streaming, allows the event to bring together a large community: speedrun enthusiasts, members of the French Restream community, as well as donors and the general public. For organizers, each run is an opportunity to raise broad awareness of the issues involved in brain research.
Neuroscience in Focus
The educational dimension is an integral part of Interglitches. Over the weekend, several researchers from the Brain Institute took the opportunity to present their work and discuss the state of the art in neurological and psychiatric diseases. Exchanges with streamers, viewers help to make science accessible, to explain the challenges that lie ahead, and to demonstrate in concrete ways how donations support these projects.
The 2025 edition also marks a significant increase in mobilization. In total, more than €25,000 was raised through online donations, ticketing and the shop. This funding will directly support research conducted by the Brain Institute. This support is invaluable: it supports ongoing scientific projects, opens up new avenues of exploration and gives teams new means to better understand the brain and its pathologies, with a view to developing therapeutic solutions. For the scientists present, this weekend was an opportunity to remind that every donation counts, regardless of its amount, and that the generosity of the gaming community contributes very directly to the advancement of knowledge.
A must-see
Interglitches has become, in five years, a must for Paris Brain Institute. The event illustrates how sometimes distant worlds can come together and create a common momentum for a cause. The strength of the marathon lies as much in the quality of its programming as in the commitment of the French Restream volunteer team, which organises for several months the technical preparation, the coordination with the players, the scheduling of the lives and the running of the weekend. Their professionalism and enthusiasm are acknowledged every year by the participants and our teams.
The public also responded, both online and in the auditorium. The on-site access, offered via an online ticket office, allows spectators to experience the event as close as possible to the players, to feel the intensity of each attempt and to exchange directly with the members of the French Restream as with the scientists. These meetings create a special bond and strengthen understanding of the mission of the Brain Institute: to advance research, accelerate discovery and improve the lives of people affected by nervous system disease.
With this fifth edition, Interglitches confirms its importance in the video game charity landscape.
Paris Brain Institute would like to extend its sincere thanks to all of the participants, both on-site and online donors, for their commitment. Their presence and support remind us that we have a common goal: to advance research to better understand the brain and to offer innovative solutions to patients.
The French Restream charity video and play marathon for the benefit of Paris Brain Institute brings together the biggest runners in France every year.
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