DODET Pauline
Title: PhD, PH
Function: PI
Affiliated entities AP-HP
Research course
2022-2024: PhD (ED3C, Sorbonne University, Paris, France) at Paris Brain Institute (supervisor: Isabelle Arnulf and Emmanuel Flamand-Roze, Mov’it Team), topic : The contribution of sleep in predicting the progression of Parkinson's disease
2014-2024: clinical researcher, member of the Mov’it team (Marie Vidailhet and Stephane Lehericy), Paris Brain Institute, Paris
Feb 2022 – Aug 2023: Visiting Scholar, Stanford Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, CA, USA
2013: Master of Neurosciences (MSc), Sorbonne University, Paris, France ; Research internship at Paris Brain Institute (supervisor: Isabelle Arnulf, Mov’it Team), topic: “What is the impact of dreaming on breathing and heart rate in REM sleep? Study of autonomic control during REM sleep using the model of lucid dreaming”.
Medical course
Since 2016: Full time senior neurologist in the Sleep disorder clinic (Pr Arnulf), Pitié-Salpêtrière hospital, APHP-Sorbonne University, Paris, France
2014-2016: Neurology resident (Chef de clinique – Assistant des Hôpitaux), Neurology Department (Pr Lubetzki), Pitié-Salpêtrière hospital and Pierre et Marie–Curie, Paris 6 University (Now Sorbonne University)
2009-2014: Interne des Hôpitaux de Paris, spécialité Neurologie (ie, Neurology residency) (University of Le Kremlin-Bicêtre , Paris, France)
2003-2009: First cycle of medical studies, Burgundy university, Dijon
The relationship between sleep and neurodegenerative diseases is complex and bidirectional. Neurodegeneration can disrupt sleep-wake circuits and physiological sleep mechanisms, leading to disorders such as REM sleep behavior disorder in Parkinson’s disease. Beyond these perceptible symptoms, sleep dysfunction may also exacerbate underlying pathophysiological processes. Clinically, early identification and longitudinal tracking of sleep disturbances are crucial for patient management. From a research perspective, sleep analysis provides a unique window into brain function, reflecting physiological integrity and associated processes. I integrate multimodal approaches—including polysomnography, clinical assessment, and imaging—within multiple neurodegenerative disease cohorts in collaboration with the neurology department and the Paris Brain Institute.