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Emmanuel FLAMAND-ROZE

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Photo d'Emmanuel FLAMAND-ROZE

Emmanuel FLAMAND-ROZE

Title: Project Sponsor, MD, PhD, PU-PH

Function: PI

Affiliated entities Sorbonne Université, AP-HP

Biography
Biography

He is very involved in the clinical care of patients with Parkinson's disease and other movement disorders at the movement disorders clinic of the Salpêtrière hospital in Paris. It has also developed a program to optimize the transition of children and young adults with chronic neurological diseases between pediatric and adult services. These main areas of research are neurodevelopmental disorders of movement. He is studying the clinical aspects, genetic causes and neurophysiological mechanisms underlying these disorders. He is also very involved in the study of experimental therapeutics and pilot studies to test them. He has published numerous articles on these topics (183 peer-reviewed articles). He received an award from the French Society of Neurology for his work on myoclonus-dystonia, the Dystonia Coalition's "pilot project" award for a project studying the role of the cerebellum in focal dystonia, and the Breughel Prize for a project studying agentivity in dystonic patients. Finally, he has a keen interest in teaching and has developed an innovative simulation-based medical education program ("The Move") to teach semiology in neurology to medical students at the Pierre and Marie Curie University in Paris. The programme has already started in Dublin (Ireland) and is to be implemented in other French and European universities. It was presented at the third meeting of the European Academy of Neurology in 2017 and was presented at the meeting of the European Academy of Neurology.

Research
Research
  • Principal Investigator 2011-2016: "Lateralization of motor control: the mirror movement paradigm"; Grant from the Inserm-COSSEC Brain Research Foundation and Fellowship
  • "A randomized, controlled, double-blind, crossover trial of zonisamide in myoclonus-dystonia"; PHRC Grant (AOR10029)
  • Principal Investigator 2011-2014: "Cerebellum and cortical plasticity: the case of focal dystonia"; Grant from the Dystonia Coalition (NS065701)
  • Principal Investigator 2014-2015: "Identification of new genes involved in paroxysmal kinesiogenic dyskinesia"; grant from the Rare Diseases Foundation
  • "Randomized, controlled, double-blind, cross-over trial of triheptanoin in the alternate hemiplegia of the child"; Grant from the Association Française de l'Hémiplegie Alternante.
  • Co-Principal Investigator 2017-2019: "Identification of neuronal mechanisms of agency in dystonia"; Grant from AMADYS (Breughel Prize 2017)

Team(s)

Team

Mov’It : mouvement, investigations, thérapeutique, mouvement normal et anormal : physiopathologie et thérapeutique expérimentale

Team leader(s) Read more