Marie-Claude POTIER
Title: PhD
Function: Team Leader, PI
Biography
Marie-Claude Potier is co-leader of the team on Alzheimer’s Disease and Prion Diseases at Paris Brain Institute and Director of Research at the CNRS. She holds a Ph.D. in Pharmacy (1983) and a Ph.D. in Neuropharmacology from Pierre and Marie Curie University (1988). She is a member of the American Society for Neuroscience, the International Society to Advance Alzheimer’s Research and Treatment, and serves on the Board of Directors of the Society for Neurosciences. She is also an external expert reader for several international newspapers and national and international agencies and foundations. In 2005, she received the Dagnan Bouveret Prize from the Institut de France.
Research
Molecular and Cellular Biology, Down Syndrome and Alzheimer’s Disease The team of Marie-Claude Potier and Stéphane Haïk is interested in the role of lipids, particularly cholesterol and Apolipoprotein E (ApoE), in the secretion and neural transport of Aß peptide, in the endosomal changes that occur in early disease, and in the mechanisms of Aß peptide toxicity identified in vivo. Dr. Haïk’s team is studying the development of pre-mortem diagnostic procedures for prion diseases, the characterization of emerging human prion strains, and the molecular and cellular mechanisms determining the selection, spread and pathogenicity of prion strains in the human brain.