Scientific lectures: Origins of Inhibitory Neuron Identity in the Developing Forebrain

The developing brain generates a remarkable diversity of neuronal cell types from a limited pool of progenitors. A central challenge is to understand how spatial cues and gene regulatory mechanisms shape these lineage decisions in vivo. In this talk, I will present the ganglionic eminence as a powerful developmental model system, and show how combining single-cell genomics, lineage tracing, and in vivo perturbation allows us to link regulatory logic to cell-type specification and ultimately circuit integration. This framework provides new insight into how neuronal diversity arises during development, and how its disruption contributes to neurodevelopmental disorders.

Hosted by Stéphanie BAULAC and Bassem HASSAN

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Conference location

Please join the conference in Paris Brain Institute auditorium.