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Bâtiment Institut du cerveau

NERV

Systems neuroengineering to model and interface brain networks

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Fabrizio De Vico Fallani
DE VICO FALLANI Fabrizio

PhD, CR1, PI, INRIA

Team presentation

The NERV team is dedicated to exploring how the brain functions as a complex network. Put simply, they aim to "read" and "understand" brain signals to create tools that could one day help people with brain disorders. Their main goal is to design technologies that enable computers to connect to the brain—known as Brain-Computer Interfaces (BCIs)—in a gentle and non-invasive manner, making everyday life easier for those suffering from neurological disorders.

 

Complete Description
Complete Description

The NERV team aspires to develop cutting-edge analytical tools and innovative technological solutions to decrypt brain functions. Focusing on the connectivity networks that govern the brain, the team seeks to understand how these networks operate and how they can sometimes become dysregulated. Their research primarily aims to monitor these dysfunctions and, where possible, repair them. To achieve this, they work on enhancing non-invasive brain-computer interfaces (BCIs), which represent a promising bridge between technology and our understanding of the brain.

Objectives
Objectives
  • Multiscale Network Analysis: By studying the brain at various levels of detail, they aim to identify functional patterns that are characteristic, whether normal or pathological.
  • Geometrical Network Embedding and Integration: The team explores new ways to represent these networks to simplify their study and improve comparisons.
  • Multimodal Data Fusion: By integrating data from various neuroimaging techniques, they aim to enhance the efficiency of BCIs through machine learning.
  • Hybrid Brain-Computer Interfaces: Their research focuses on how these systems can improve interactions between the human brain and machines.
  • Network-Based Improvements for BCIs: They believe that brain network characteristics can provide valuable insights for better decoding users’ mental intentions.

Current projects within the team tackle questions such as multiscale brain network modeling, detecting abnormal state transitions in non-Euclidean spaces, and developing innovative hybrid controls for brain-computer interfaces. Through this research, the NERV team hopes to transform our ability to treat and manage neurological disorders by providing innovative technological solutions that could revolutionize the field of brain health.

Principales publications
Principales publications
  1. Ben Messaoud R., Le Du V., Bousfiha C., Corsi M.C., Gonzalez-Astudillo J., Kaufmann B.C., Venot T., Couvy-Duchesne B., Migliaccio L., Rosso C., Bartolomeo P., Chavez M. & De Vico Fallani F. (2025). Low-dimensional controllability of brain networks. PLoS Comput Biol, 21(1), e1012691. https://doi.org/10.1371/journal.pcbi.1012691
  2. Presigny C., Corsi M.C. & De Vico Fallani F. (2024). Node-layer duality in networked systems. Nature Communications, 15, 6038. https://doi.org/10.1038/s41467-024-50176-5
  3. Venot T., Desbois A., Corsi M.C., Hugueville L., Saint-Bauzel L. & De Vico Fallani F. (2024). Intentional binding for noninvasive BCI control. J Neural Eng, 21(4). https://doi.org/10.1088/1741-2552/ad628c
  4. Dichio V. & De Vico Fallani F. (2024). Exploration-Exploitation Paradigm for Networked Biological Systems. Physical Review Letters, 132(9), 098402. https://doi.org/10.1103/physrevlett.132.098402
  5. Corsi M.C., Chevallier S., De Vico Fallani F. & Yger F. (2022).  Functional connectivity ensemble method to enhance BCI performance (FUCONE). IEEE Trans Biomed Eng, 69(9). https://doi.org/10.1109/tbme.2022.3154885
  6. Obando C., Rosso C., Siegel J., Corbetta M. & De Vico Fallani F. (2022). Temporal exponential random graph models of longitudinal brain networks after stroke. J R Soc Interface, 19: 20210850. https://doi.org/10.1098/rsif.2021.0850

Team members

Fabrizio De Vico Fallani
DE VICO FALLANI Fabrizio

PhD, CR1, PI, INRIA

Mario CHAVEZ
CHAVEZ Mario

Dr, PI, CNRS

News from the team

Présentation lors de la visite international
A special international visit: members and friends of the International Olympic Committee discover Paris Brain Institute
On Wednesday July 31, the Institute had the pleasure of welcoming a special group of visitors: members of the International Olympic Committee (IOC) and their friends and families.
09.08.2024 Institutional
Des lumières vu d'en dessous
Three New ERC Laureates at Paris Brain Institute
Fabrizio DE VICO FALLANI, Chargé de Recherche INRIA and Daniel MARGULIES, Chargé de Recherche CNRS have obtained the ERC Consolidator Grants, Jaime DE JUAN SANZ was rewarded by the ERC Starting grant.
12.12.2019 Events
Modélisation en 3D
A new model to predict brain development
From the very first weeks of life, countless connections are forged between neurons to ensure the propagation of nerve signals. These connections gradually shape the final architecture of the brain, known as the connectome. Our ability to perform...
03.08.2024 Research, science & health
cerveau
Computational model of brain complexity and function, a new research perspective
In a recent paper, published in Reviews of Modern Physics, Charley Presigny and Fabrizio de Vico Fallani (Inria) from the ARAMIS team from the Paris Brain Institute present a new mathematical model to decipher the brain organization and function in...
08.08.2022 Research, science & health
cerveau
A new mathematical model of brain connectivity after stroke
In a recent paper published in the Journal of Royal Society Interface, Catalina Obando, Charlotte Rosso (Sorbonne Université, AP-HP) Fabrizio de Vico Fallani (Inria) and their collaborators at the Brain Institute propose a new approach to...
04.22.2022 Research, science & health
modélisation mathématique
Stepwise target controllability identifies dysregulations of macrophage networks in multiple sclerosis
Violetta ZUJOVIC, INSERM researcher and Team Leader and Fabrizio De VICO FALLANI, INRIA researcher at the Paris Brain Institute just published in Network Neuroscience. Identifying the nodes able to drive the state of a network is crucial to...
05.06.2021 Research, science & health
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