Brain tumours are generally not hereditary outside specific contexts, however, genetic markers (polymorphisms) have been identified that slightly increase the risk of developing this type of cancer in an individual.
The causes of brain tumours
This genetic predisposition is expressed only after exposure to one or more environmental factors that have not yet been clearly identified.
At Paris Brain Institute
The search for polymorphisms involved in the predisposition to develop brain tumours requires the study of a very large population of patients. The research team of Prof. Marc SANSON and Dr. Emmanuelle HUILLARD is participating in this research as part of an international consortium. In 2017, a genome-wide study was carried out on a population of 12496 patients with brain tumours and 18 190 healthy controls.
To date, 25 polymorphisms have been identified as increasing the risk of developing a brain tumour.
