Brain tumors are not usually hereditary, except in certain specific cases. However, researchers have identified genetic markers (polymorphisms) that cause a very slight increase in the risk of developing this type of cancer in a given individual.
The Causes of Brain Tumors
This genetic predisposition only manifests after exposure to one or more environmental factors that have not yet been identified with certainty.
At Paris Brain Institute
The search for polymorphisms involved in the predisposition to develop brain tumors requires the study of a very large population of patients. The research team led by Prof. Marc Sanson and Dr Emmanuelle Huillard is taking part in this research as part of an international consortium. In 2017, a genome-wide study was carried out on a population of 12,496 patients with brain tumors and 18,190 healthy controls.
To date, 25 polymorphisms have been identified as increasing the risk of developing a brain tumor.
