Frontotemporal Degenerations and the Logopenic Variant of Primary Progressive Aphasia
A study published in the journal Neurology, conducted by Dario Saracino, Isabelle Le Ber (AP-HP), and their collaborators, highlights the importance of testing for mutations in a specific gene, the progranulin gene (GRN), in order to distinguish...
07.20.2021
Research, science & health
GAB1, a good biomarker for Hedgehog-activated anterior skull base meningiomas
A study conducted by Julien Boetto and Franck Bielle (Sorbonne University. AP-HP) of the " Genetics and Development of Nervous System Tumours" team at the Paris Brain Institute highlights the potential of GAB1 as a new biomarker for Hedgehog...
06.14.2021
Research, science & health
Stepwise target controllability identifies dysregulations of macrophage networks in multiple sclerosis
Violetta ZUJOVIC, INSERM researcher and Team Leader and Fabrizio De VICO FALLANI, INRIA researcher at the Paris Brain Institute just published in Network Neuroscience. Identifying the nodes able to drive the state of a network is crucial to...
05.06.2021
Research, science & health
A new non-invasive therapy for the treatment of Primary Orthostatic Tremor (POT): Trans-spinal electrical stimulation
Primary orthostatic tremor (POT) is a rare and poorly understood neurological disorder. It presents as a very rapid tremor (not visible to the naked eye) of the legs and trunk, causing a feeling of instability and fear of falling. The symptoms appear...
04.19.2021
Research, science & health
Specific patterns identified by electroencephalography in patients infected with sars-cov-2
Neurological disorders have been reported in patients with Covid-19. Researchers and clinicians from the Paris Brain Institute and the Hôpital Pitié-Salpêtrière AP-HP have shown the interest of combining different examinations with...
04.08.2021
Research, science & health
Definition of new forms of the behavioural variant of frontotemporal degenerations (FTD)
Frontotemporal degeneration (FTD) is a complex neurodegenerative disorder that can manifest itself through a wide range of symptoms. Valérie Godefroy, postdoctoral researcher in the Frontlab, under the supervision of Lara Migliaccio, and her...
05.05.2021
Research, science & health
Non-invasive brain stimulation for neurodegenerative diseases
Non-invasive brain stimulation is a rapidly expanding field with promising leads for the treatment of neurodegenerative diseases. Within the Frontlab of the Paris Brain Institute, Clara Sanches, a doctoral student, Dr. Lara Migliaccio (Inserm) and Dr...
03.25.2021
Research, science & health
Obesity and response to food marketing
Researchers from the Paris Brain Institute, INSEAD, the Nutrition Department of the Pitié-Salpêtrière Hospital (AP-HP/Sorbonne Université), EPHE and the University of British Columbia, provide new evidence for a reciprocal relationship between...
03.13.2021
Research, science & health
Weight loss and reward brain system
A study conducted by Liane Schmidt (INSERM) and Hilke Plassmann (INSEAD’s Octapharma Chaired Professor of Decision Neuroscience) both researchers at the Paris Brain Institute establishes for the first time a link between weight loss, the connectivity...
03.12.2021
Research, science & health
New insights on a major protein involved in Alzheimer’s disease
New study conducted by Irini Kessissoglou in the “Brain development” team headed by Bassem Hassan at Paris Brain Institute reveals new functions for the Amyloid Precursor Protein (APP) homologue in drosophila. Results are published in PLOS Biology.
12.16.2020
Research, science & health
Discovery of a plasma signature of fronto-temporal degeneration and amyotrophic lateral sclerosis linked to a mutation of the C9orf72 gene
A joint study by teams from the Paris Brain Institute at the Pitié-Salpêtrière hospital and from Inria (Rennes and Paris centers) has revealed for the first-time plasma microRNA signatures in individuals with or presymptomatic of fronto-temporal...
12.04.2020
Research, science & health
Making sense of the world: the cerebral bases of abstraction
A study conducted at the Zuckerman Institute of Columbia University (USA) by Jerome Munuera, co-first author and researcher at the Paris Brain Institute, and his collaborators, led to the development of the first functional model of abstraction in...
11.19.2020
Research, science & health