Skip to main content

Or 34,00 After 66% tax deduction

I make a monthly donation I make an IFI donation
Un écran d'ordinateur avec une image médicale

Bidding Program Big Brain Theory

Exploring new avenues

Last update: 15/12/2025 Reading time: 1min
Retour à la recherche

Launched in June 2015 by Paris Brain Institute, the Big Brain Theory (BBT) programme funds innovative, interdisciplinary, high-risk projects co-sponsored by various in-house research teams.

Origins of the programme

Origins of the programme

The Big Brain Theory program was born out of an original idea: what if it were possible to do research differently, more boldly and interdisciplinarily, to find tomorrow’s treatments for brain diseases?

Why "Big Brain"? Because the challenges of the brain are immense, and because so are our ambitions to serve patients.

Why “Theory”? Because we want to propose unexplored ideas and new ways to advance our understanding of our brain.

This research program now includes many bold and innovative projects, some of which have already led to major discoveries.

Exploring new avenues

Exploring new avenues

Since its inception, the Big Brain Theory program has provided grants for innovative, interdisciplinary new projects in neuroscience for researchers and clinicians at the Institute.

Paris Brain Institute hopes that each "Big Brain Theory" will aim to engage each Principal Investigator and Platforms in a collaborative effort to broaden the impact of individual-level research and develop new pioneering projects that translate into collective advances that will become the symbols of the Institute.

News that might interest you

Deux nouvelles certifications pour les plateformes de l’Institut du Cerveau
Two new certifications for Paris Brain Institute’s core facilities
Paris Brain Institute’s core facilities were recently awarded two new certifications: ISO 9001 certification for ICM.Quant and ISO 20387 certification for its DNA & Cell Bank.
11.14.2025 Institutional
La dépression résistante possède une signature moléculaire spécifique
Treatment-resistant depression identified as a distinct molecular subtype
An international study published in Brain, Behavior, and Immunity shows that patients with treatment-resistant depression (TRD) have a unique biology, different from those who respond to standard therapies. More than 5,000 genes were found to behave...
11.03.2025 Research, science & health
La qualité des mitochondries durant le neurodéveloppement est cruciale pour la santé cérébrale
Mitochondrial quality during neurodevelopment is crucial for brain health
The anomalies underlying neurodegenerative diseases may arise during development—decades before the first symptoms appear. This hypothesis is gaining traction thanks to a new study published in Nature Communications. According to researchers from the...
10.20.2025 Research, science & health
La bibliothèque de Babel
Mental Time Travel: A New Case of Autobiographical Hypermnesia
Remembering past events in minute detail, revisiting them methodically, and reliving past emotions—this is the peculiarity of people with an exceptional memory of their own lives, known as autobiographical hypermnesia, or hyperthymesia. This...
08.28.2025 Research, science & health
sequencage adn
Intellectual development disorders: two new genes under the microscope
A Franco-German international research team has identified two new genes that play a role in the onset of intellectual development disorders (IDD), also known as intellectual disabilities. Researchers have successfully developed two new types of test...
12.08.2025 Research, science & health
Troubles du Développement Intellectuel
The "RNU-Splice" project receives support from the health sponsorship of AXA Mutuals
Intellectual development disorders (IDD) affect 2 to 3 per cent of the population and are characterized by impaired cognitive functions, impacting learning. TDI thus has an impact on coping skills with implications for daily life and is a major...
10.08.2025 Support
See all our news