Molecular characterization of primary lymphomas of the central nervous system towards a better prediction of evolution and personalized treatments
Researchers and clinicians from the research team co-directed by Prof. Marc SANSON and Emmanuelle HUILLARD at the Paris Brain Institute have just identified four molecular profiles of primary central nervous system lymphoma (PCNSL) that could predict...
12.07.2022
Research, science & health
Ketamine and depression: a mechanism of the antidepressant effect reveal
Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant. Ketamine, usually used as an anesthetic, was administered...
10.06.2022
Research, science & health
A new anti-inflammatory mechanism identified
The team " Plasticity and regeneration of myelin" co-directed by Brahim NAIT-OUMESMAR, Inserm Research Director at the Paris Brain Institute - in collaboration with Angela Giangrande's team (IGBMC, Illkirch) has just demonstrated that the Gcm2 gene...
10.25.2022
Research, science & health
How to discern impulsivity from alteration of anticipation?
In everyday life, we all need to anticipate our actions. On the road, for example, we need to start or cross when the light turns green. While the light is red, our brain prepares to act as quickly as possible as soon as the color changes because we...
10.13.2022
Research, science & health
Cognitive fatigue: new insight on biological mechanisms
A study by the Brain Institute (ICM/Inserm/CNRS/Sorbonne University/AP-HP) establishes for the first time the link between the onset of cognitive fatigue and the accumulation of a neurotransmitter called glutamate in a particular region of the brain...
12.11.2022
Research, science & health
In the brains of procrastinators
A research team from Inserm, CNRS, Sorbonne University and AP-HP at the Paris Brain Institute in Paris just deciphered how our brain behaves when we procrastinate. The study, conducted in humans, combines functional imaging and behavioral testing. It...
10.12.2022
Research, science & health
Transcranial Magnetic Stimulation, what happens in the brain?
Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation procedure that uses transient electromagnetic fields to act in a focused manner on a particular brain region. It can be used as a therapy for depression, Parkinson's disease or...
10.06.2022
Research, science & health
Genetics of early-onset parkinsonism with intellectual disability
A research team from the Paris Brain Institute (Inserm/CNRS/Sorbonne University/AP-HP) just identified mutations in familial cases with early-onset Parkinsonism and intellectual disability. Genetic studies on two affected siblings pairs highlighted...
09.29.2022
Research, science & health
An open-source algorithm to help Alzheimer's disease diagnosis
The diagnosis of atypical forms of Alzheimer's disease is still sometimes difficult. Researchers from Paris Brain Institute have developed an automated algorithm to correlate the specificities of brain lesions with the symptoms associated with these...
09.18.2022
Research, science & health
Computational model of brain complexity and function, a new research perspective
In a recent paper, published in Reviews of Modern Physics, Charley Presigny and Fabrizio de Vico Fallani (Inria) from the ARAMIS team from the Paris Brain Institute present a new mathematical model to decipher the brain organization and function in...
08.08.2022
Research, science & health
Alzheimer's disease, a complex genetic susceptibility
Although Alzheimer's disease is not inherited in 95% of cases, nearly 75 genetic susceptibility factors - that is, factors that increase the risk to develop the disease - or protective factors - that decrease the probability to be affected - have...
07.11.2022
Research, science & health
Status Epilepticus: new biomarkers to improve the prognosis of patients admitted to the ICU
A major neurological emergency, status epilepticus is defined as a persistent epileptic seizure. Exposing patients to irreversible brain lesions that cause serious cognitive sequelae, it requires intensive care, which may lead to sedation (artificial...
07.06.2022
Research, science & health