Research, science & health

A study by the Brain Institute (ICM/Inserm/CNRS/Sorbonne University/AP-HP) establishes for the first time the link between the onset of cognitive fatigue and the accumulation of a neurotransmitter called glutamate in a particular region of the brain...

A research team from Inserm, CNRS, Sorbonne University and AP-HP at the Paris Brain Institute in Paris just deciphered how our brain behaves when we procrastinate. The study, conducted in humans, combines functional imaging and behavioral testing. It...

Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation procedure that uses transient electromagnetic fields to act in a focused manner on a particular brain region. It can be used as a therapy for depression, Parkinson's disease or...

A research team from the Paris Brain Institute (Inserm/CNRS/Sorbonne University/AP-HP) just identified mutations in familial cases with early-onset Parkinsonism and intellectual disability. Genetic studies on two affected siblings pairs highlighted...

The diagnosis of atypical forms of Alzheimer's disease is still sometimes difficult. Researchers from Paris Brain Institute have developed an automated algorithm to correlate the specificities of brain lesions with the symptoms associated with these...

In a recent paper, published in Reviews of Modern Physics, Charley Presigny and Fabrizio de Vico Fallani (Inria) from the ARAMIS team from the Paris Brain Institute present a new mathematical model to decipher the brain organization and function in...

Although Alzheimer's disease is not inherited in 95% of cases, nearly 75 genetic susceptibility factors - that is, factors that increase the risk to develop the disease - or protective factors - that decrease the probability to be affected - have...

A major neurological emergency, status epilepticus is defined as a persistent epileptic seizure. Exposing patients to irreversible brain lesions that cause serious cognitive sequelae, it requires intensive care, which may lead to sedation (artificial...

Jean-Léon Thomas' group (Inserm, Paris Brain institute) just published a 3D mapping of the meningeal lymphatic network and the associated cerebrospinal fluid (CSF) drainage, both in mice and in humans. Beyond the identification of highly conserved...

Coming up with a creative idea requires us to draw on all our previous knowledge. But how does this happen in our mind and in our brain? Emmanuelle Volle's group (Inserm) at the Frontlab of the Paris Brain Institute, in collaboration with the...

The team "Motivation, Brain and Behavior", co-directed by Mathias Pessiglione (Inserm) at the Paris Brain Institute, proposes in a study published in the Journal of Neuroscience a new approach to understand how our prefrontal cortex makes decisions.

Thanks to an approach combining behavioral assessment and brain imaging, a study conducted by the Paris Brain Institute's FrontLAB has led to a better characterization of a major symptom of frontotemporal degeneration, disinhibition. These results...