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Research, science & health

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Computational model of brain complexity and function, a new research perspective
In a recent paper, published in Reviews of Modern Physics, Charley Presigny and Fabrizio de Vico Fallani (Inria) from the ARAMIS team from the Paris Brain Institute present a new mathematical model to decipher the brain organization and function in...
08.08.2022 Research, science & health
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Alzheimer's disease, a complex genetic susceptibility
Although Alzheimer's disease is not inherited in 95% of cases, nearly 75 genetic susceptibility factors - that is, factors that increase the risk to develop the disease - or protective factors - that decrease the probability to be affected - have...
07.11.2022 Research, science & health
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Status Epilepticus: new biomarkers to improve the prognosis of patients admitted to the ICU
A major neurological emergency, status epilepticus is defined as a persistent epileptic seizure. Exposing patients to irreversible brain lesions that cause serious cognitive sequelae, it requires intensive care, which may lead to sedation (artificial...
07.06.2022 Research, science & health
réseau lymphatique
3D mapping of the meningeal lymphatic network reveals new mysteries
Jean-Léon Thomas' group (Inserm, Paris Brain institute) just published a 3D mapping of the meningeal lymphatic network and the associated cerebrospinal fluid (CSF) drainage, both in mice and in humans. Beyond the identification of highly conserved...
07.05.2022 Research, science & health
Des personnages avec une ampoule qui symbolise la créativité
How do we explore our knowledge to be creative?
Coming up with a creative idea requires us to draw on all our previous knowledge. But how does this happen in our mind and in our brain? Emmanuelle Volle's group (Inserm) at the Frontlab of the Paris Brain Institute, in collaboration with the...
06.29.2022 Research, science & health
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Decision-making: a new distribution of tasks in our prefrontal cortex?
The team "Motivation, Brain and Behavior", co-directed by Mathias Pessiglione (Inserm) at the Paris Brain Institute, proposes in a study published in the Journal of Neuroscience a new approach to understand how our prefrontal cortex makes decisions.
06.23.2022 Research, science & health
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A better characterization of disinhibition in frontotemporal degeneration
Thanks to an approach combining behavioral assessment and brain imaging, a study conducted by the Paris Brain Institute's FrontLAB has led to a better characterization of a major symptom of frontotemporal degeneration, disinhibition. These results...
06.20.2022 Research, science & health
schéma
Visual mental imagery: a patient case suggests a new key brain network
Every day, we call upon a unique capacity of our brain, visual mental imagery, which allows us to visualise images, objects or people 'in our heads'. Based on the recent case of a patient with a specific brain lesion, Paolo Bartolomeo's group (Inserm...
06.09.2022 Research, science & health
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Predicting the risk of developing Alzheimer's disease using genetic markers?
Although Alzheimer's disease is not hereditary in 99% of cases, genetic factors can increase the risk of developing it. The "Alzheimer's disease, prion diseases" team, co-directed by Marie-Claude Potier (CNRS) at the Paris Brain Institute, has...
03.24.2022 Research, science & health
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A new statistical method for improved brain mapping
Brain mapping consists in finding the brain regions associated with different traits, such as diseases, cognitive functions, or behaviours, and is a major field of research in neuroscience. This approach is based on statistical models and is subject...
05.23.2022 Research, science & health
confinement et créativité
How the first lockdown of the COVID-19 pandemic changed our creativity
Covid-19 took us by surprise and the exceptional situation of the first lockdown required great capacities of adaptation, in particular for our brain. A study conducted at the Paris Brain Institute (Inserm/CNRS/Sorbonne University/AP-HP) has just...
05.10.2022 Research, science & health
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A new mathematical model of brain connectivity after stroke
In a recent paper published in the Journal of Royal Society Interface, Catalina Obando, Charlotte Rosso (Sorbonne Université, AP-HP) Fabrizio de Vico Fallani (Inria) and their collaborators at the Brain Institute propose a new approach to...
04.22.2022 Research, science & health