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Research, science & health

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World Parkinson's Day 2022: where does research stand?
On the occasion of World Parkinson's Day, which will be held on 11 April 2022, the Paris Brain Institute takes stock of the latest advances in research and the challenges that remain in the fight against the second most common neurodegenerative...
04.11.2022 Research, science & health
mécanismes
Discovery of the mechanisms behind epileptic seizures in autoimmune encephalitis
An unprecedentedly precise exploration of the molecular and electrophysiological basis of a form of autoimmune encephalitis, conducted by the " Cellular Excitability and Neuronal Network Dynamics" team at the Paris Brain Institute, elucidates for the...
04.07.2022 Research, science & health
image
Restoring consciousness through deep brain stimulation
A research team involving neuroscience researchers and clinicians from the CEA, the Foch Hospital, the University of Versailles Saint-Quentin-en-Yvelines, Inserm, the Collège de France and the Paris Brain Institute, has provided proof that deep brain...
03.21.2022 Research, science & health
image cerveau
Hypnotic suggestion informed by neuroscience
Within the walls of the Pitié-Salpêtrière AP-HP hospital, where Charcot explored hypnosis at the end of the 19th century, the research team led by Professor Lionel Naccache at the Paris Brain Institute (Inserm/CNRS/Sorbonne University), has just...
03.21.2022 Research, science & health
First demonstration of the neuroprotective effect of remyelination in multiple sclerosis patients
First demonstration of the neuroprotective effect of remyelination in multiple sclerosis patients
In an article recently published in the European Journal of Neurology, Vito Ricigliano (AP-HP), Benedetta Bodini (AP-HP/Sorbonne University) and their collaborators at the Paris Brain Institute, demonstrate the protective effect of myelin repair on...
02.24.2022 Research, science & health
Cerveau
Identification of new risk factors or early signs of Alzheimer's disease
What risk factors are associated with Alzheimer's up to 15 years before the onset of the first symptoms? This is a vital question for specialists of this neurodegenerative disease – which develops over many years before becoming clinically visible –...
02.23.2022 Research, science & health
Cellule microgliale
Bone marrow transplant: What is the impact of chemotherapy on the brain?
More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases. Before the cells are transplanted, the patients are given chemotherapy to destroy the immune...
02.21.2022 Research, science & health
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Artificial Intelligence-based MRI biomarker of Isolated REM Sleep Behavior Disorder and Parkinson's disease
Rahul Gaurav, a research Engineer in the MOV’IT team led by Pr. Stéphane Lehéricy and Pr. Marie Vidailhet, at the Paris Brain Institute, developed an artificial intelligence framework to investigate fully automatic neurodegeneration in the substantia...
02.18.2022 Research, science & health
emotions sommeil
Our eye movements reveal our emotions during sleep
Dream or nightmare, our sleep is often rich in emotions. A study conducted by Jean-Baptiste Maranci (Sorbonne University), Isabelle Arnulf (AP-HP/Sorbonne University) and their collaborators at Paris Brain Institute and the Pitié-Salpêtrière Hospital...
02.16.2022 Research, science & health
créativité
How our knowledge of the world embedded in brain connectivity shapes our creativity
The group of Emmanuelle Volle at Paris Brain Institute and their international collaborators established for the first time a link between real-life creativity, semantic memory structure, and brain functional connectivity. The results, published in...
02.05.2022 Research, science & health
Projections of nesting-activated neurons throughout the brain, showing the extent of the regions contacted by these neurons. The image is obtained from 3D light-sheet imaging allowing the reconstruction of fibre trajectories in the brain at micrometric resolution.
Discovery of a novel role for an elusive brain region in maternal behaviors in mice
Gestation leads to a modification of brain circuits and behaviors such as nesting within the animal kingdom. The underlying biological, neural and hormonal mechanisms have been unknown until now. In a new study, the team led by Nicolas Renier (Inserm...
02.04.2022 Research, science & health
cerveau
Spinocerebellar ataxia type 2: a therapeutic trial opens new avenues
A clinical trial conducted by Prof. Alexandra Durr's team (Sorbonne University.AP-HP) at the Paris Brain Institute and the Pitié-Salpêtrière Hospital AP-HP shows that despite the hopes raised in recent years, riluzole does not improve the clinical or...
01.19.2022 Research, science & health