Welcome to the “news” section of our website, where you'll find all the latest publications on our advances in research (Alzheimer's, Parkinson's, Charcot's disease, etc.), our upcoming events, etc.
A recent study carried out by Frédéric Darios in the team led by Alexis Brice at the Institut du Cerveau - ICM highlights the importance of spatacsin, a protein affected in pathologies such as hereditary spastic paraplegia.
Hereditary spastic paraplegias are a heterogeneous group of pathologies and share clinical similarities with other neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).
A team at the Institut du Cerveau - ICM showed that different mutations of one gene, ALDH18A1, are associated with several types of hereditary spastic paraplegias and different modes of transmission. Moreover, the researchers identified a new blood...
A research team of the Institut du Cerveau - ICM institute took part to an international study identifying 18 new genes implicated in hereditary spastic paraplegias (HSP). This work, published on January the 31th on the prestigious website of the...
Hereditary Spastic Paraplegia (HSP) are a genetically heterogeneous group of invalidating neurological disorders characterized by a progressive difficulty walking due to stiff legs (spastic) and additional neurological signs like epilepsy, ataxia...
A research team directed by Giovanni Stevanin and Alexis Brice from the Brain and Spine Institute, in collaboration with other teams of the international SPATAX network (coordinator, Alexandra Durr), have identified 3 new causative genes in...