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Imagerie scientifique

Brain Development

Bassem Hassan
Bassem HASSAN

PhD, Team Leader, PI, Inserm

Team presentation

The "Brain Development" team, led by Bassem HASSAN, is interested in the formation of neurons and neural networks during brain development thanks to models of Drosophila and murine flies. The team is studying the transcriptional control of embryonic neural stem cells, as well as the emergence of visual circuits and neural networks responsible for behaviour and the transcriptional control of embryonic stem cells.

The 3 objectives of the Brain Development Team are:

  • Investigating the role of proneural proteins in the genesis of neurons
  • Demonstrate the link between neuronal excitability and individual innate behaviour
  • Understanding the function of human genes associated with pathology during brain development
Main publications

Main publications

Team members

Bassem Hassan
Bassem HASSAN

PhD, Team Leader, PI, Inserm

Photo de Carlos PARRAS
Carlos PARRAS

Project Sponsor, PhD, CR1, PI, INSERM

Laila EL KHATTABI

Genetics, PI, AP-HP

News from the team

Un visage constitué de feuille
EnCode-ID project on Intellectual Disabilities receives patronage support from Mutuelles AXA
An Intellectual Development Disorder (IDD) is a cognitive skills development disorder beginning in early childhood. Despite advances in genetics, in around 50% of cases the cause of this neurodevelopmental disorder is still not identified. The ENCode ...
11.30.2023 Support
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One, two, many, lots: fruit flies can discriminate between numerical quantities
Assessing a number of elements, whether individuals in a group, twigs in a nest, or fruit on a branch, is an essential skill in many animals. But the neural circuits on which it is based are still poorly understood. To remedy this lack of knowledge ...
07.14.2023 Research, science & health
Organoïde de cortex humain. Les cellules progénitrices corticales apparaissent en blanc, et les nouveaux neurones en vert. Les autres cellules sont marquées en magenta en arrière-plan.
Abnormalities in neurodevelopment could lay the foundations for Alzheimer’s disease
What if Alzheimer’s disease left its mark on the embryo? Khadijeh Shabani and her colleagues from the “Brain Development” team led by Bassem Hassan (Inserm) at Paris Brain Institute show that the amyloid precursor protein (APP) has a specific ...
06.19.2023 Research, science & health
Portrait Bassem Hassan
Bassem Hassan, a maestro of research
Bassem Hassan is the Paris Brain Institute’s Scientific Director and Director of Core Facilities ...
04.21.2023 Portraits
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New insights on a major protein involved in Alzheimer’s disease
New study conducted by Irini Kessissoglou in the “Brain development” team headed by Bassem Hassan at Paris Brain Institute reveals new functions for the Amyloid Precursor Protein (APP) homologue in drosophila. Results are published in PLOS Biology. ...
12.16.2020 Research, science & health
Bassem Hassan
Bassem HASSAN receives the prestigious Roger de Spoelberch prize 2019 
Paris, February 5th 2020 - Bassem Hassan, head of the "Brain Development" team and Scientific Director of the Brain and Spinal Cord Institute (Institut du Cerveau - ICM), received the Roger de Spoelberch Prize for his research project in the field of ...
02.06.2020 Events