Understanding in 2 Minutes : Epilepsy

Unlike classic epileptic seizures that last only a few seconds or minutes, " status epilepticus" refers to a state of neuronal hyperactivity in the cerebral cortex that persists for several hours or days. When this condition occurs without a readily...

Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant. Ketamine, usually used as an anesthetic, was administered...

A major neurological emergency, status epilepticus is defined as a persistent epileptic seizure. Exposing patients to irreversible brain lesions that cause serious cognitive sequelae, it requires intensive care, which may lead to sedation (artificial...

A rare and tragic consequence of epilepsy is Sudden Unexpected Death in Epilepsy (SUDEP), which occurs after a seizure. The mechanisms involved, whether respiratory, cardiac or cerebral, are not yet fully understood. However, this risk is very low...

A stage 3 clinical trial has proven the efficacy of lacosamide alone to treat focal seizures, specifically as a first-line treatment for newly diagnosed epilepsy.

During generalized seizures, in which epileptic activities affect the entire cerebral cortex, patients undergo an interruption of their conscious processes and are unable to deal efficiently with sensory stimuli. Using a genetic model of absence...