Understanding in 2 Minutes: Multiple Sclerosis (MS)

Comprendre en 2 minutes la sclérose en plaques

Bruno Stankoff, neurologist (AP-HP / Sorbonne University) and co-leader of the research team at Paris Brain Institute, explains the causes, symptoms and treatments of multiple sclerosis.

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La Sclérose en Plaques (SEP)

La Sclérose en Plaques (SEP) est la 2ième cause nationale de handicap acquis chez l’adulte jeune après les traumatismes. Elle touche aujourd’hui 120 000 personnes en France avec 3 000 nouveaux cas diagnostiqués chaque année. Cette maladie constitue...

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Monocyte – un globule blanc qui se différencie en macrophage. Crédit : Université d’Edinbourg.

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Neurone de la rétine prolongé par un long axone entouré de sa gaine de myéline. Crédit : Annie Cavanagh, Wellcome collection.

Early cortical remyelination has a neuroprotective effect in multiple sclerosis

Multiple sclerosis is a heterogeneous disease whose manifestations vary considerably from patient to patient and whose course appears, on the surface, unpredictable. Hence, it is crucial to identify the factors that drive disability progression. In a...

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What if the biological mechanisms that cause multiple sclerosis were triggered years before clinical diagnosis? This is what a team at Paris Brain Institute suggests in a new study published in Neurology. The researchers show that, on a population...

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Têtard de Xénope transgénique chez lequel la substance blanche (myéline) apparaît par fluorescence, en vert. Crédit : David Akbar (plateforme ICM Quant) et Elodie Martin (Equipe Lubetzki/Stankoff).

Multiple sclerosis: a new tool to reduce clinical failure

No treatment currently exists that can stop the silent progression of multiple sclerosis, and many promising drugs have proved ineffective in clinical trials. To reduce this failure rate and better predict the potential of candidate molecules...

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First demonstration of the neuroprotective effect of remyelination in multiple sclerosis patients

In an article recently published in the European Journal of Neurology, Vito Ricigliano (AP-HP), Benedetta Bodini (AP-HP/Sorbonne University) and their collaborators at the Paris Brain Institute, demonstrate the protective effect of myelin repair on...

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New data on inflammation in multiple sclerosis using PET-MRI

Several studies by Prof. Bruno Stankoff's team "Remyelination in multiple sclerosis: from biology to clinical translation", highlight new mechanisms of brain inflammation in multiple sclerosis, thanks to new imaging tools based on the combination of...

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