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Paris Brain Institute

is a leading scientific and medical research center dedicated to the study of the brain and the discovery of new treatments for diseases of the nervous system. 

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In the fight against Alzheimer’s, Parkinson’s, brain tumours, ALS, epilepsy, depression, stroke, multiple sclerosis… it is not just the researchers who are driving the research forward.

More information (in French)
Scientifiques et une testatrice

Our latest news

La huntingtine est une protéine indispensable au développement embryonnaire, à la formation et au maintien du tissu cérébral.
Huntington's Disease: The Energy Hypothesis Gets Traction
Huntington's disease, a rare hereditary neurological disorder, is associated with an energy deficit that precedes the onset of symptoms and is closely linked to their progression. At Paris Brain Institute, Fanny Mochel and her colleagues are testing...
02.11.2025 Research, science & health
Visuel Voeux 2025
2025: An ambitious dynamic led by Prof. Stéphanie DEBETTE, the new Executive Director of the Institute since January 1, 2025
Professor Gérard SAILLANT, President of Paris Brain Institute, extends his warmest wishes to all those who, by faithfully supporting the research carried out at the institute, enable us to make a tangible difference in our fight against brain...
01.08.2025 Institutional
À la recherche de marqueurs d’imagerie dans la démence frontotemporale
Searching for Imaging Markers in Frontotemporal Dementia
Could exploring the relationships between different brain networks help us understand frontotemporal dementia (FTD)? This neurodegenerative disease, which progresses at varying rates, is often diagnosed late—when clinical signs are already severe. At...
01.07.2025 Research, science & health
Stéphanie Debette
Professor Stéphanie Debette takes the helm of Paris Brain Institute
Appointed Executive Director of Paris Brain Institute for a five-year term, Professor Stéphanie Debette took up her new position on January 1, 2025. She succeeds Professor Alexis Brice, who has served as Executive Director since 2012.
01.07.2025 Institutional
Une chercheuse en train de travailler
Paris Brain Institute Announces Winners of the Second Edition of NeurAL, Its Acceleration Program for Innovative Projects
Paris, December 11, 2024. Identifying and supporting innovative neuroscience projects up to the creation of viable startups: this is the mission of iPEPS, Paris Brain Institute's startup studio. Through the NeurAL program, launched in 2023 and...
01.02.2025 Research applications
Monocyte – un globule blanc qui se différencie en macrophage. Crédit : Université d’Edinbourg.
Discovery of a Macrophage Anomaly in Multiple Sclerosis
Certain patients with multiple sclerosis (MS) can partially regenerate myelin—the protective sheath that surrounds nerve fibers—which is damaged during the evolution of the disease. In studying how immune cells influence this remyelination...
12.19.2024 Research, science & health
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Des mains de chercheuse qui manipulent

Research at Paris Brain Institute

Since its creation, Paris Brain Institute has placed patients at the heart of its scientific and medical strategy.

  • 846 Staff

    including 83% scientific, medical and paramedical staff (as at September 30, 2023)

  • 29 Research teams

    selected by a Scientific Advisory Board

  • 45 Nationalities

    (as at September 30, 2023)

  • 12 Technical facilities

    and biobank

Find out more

Understanding the brain

Le fonctionnement du cerveau : deux scientifiques regardent des images de cerveau
Understanding the Brain
Every day, scientific research tells us a little more about the brain, the body’s control room for all cognition, memory and emotions. From the anatomy of the brain to the latest knowledge about consciousness and the different neurological diseases...
Imagerie cérébrale Lubetzki Stankoff
Alzheimer's disease
With longer life expectancies and the biological mechanisms at the origin of neurodegenerative diseases becoming increasingly complex, it is now estimated that, in France in 2020, 1.3 million people were affected by Alzheimer’s disease. Today, more...
Imagerie cérébrale Corti Corvol Parkinson
Parkinson's disease
Parkinson’s disease is the second-most common neurodegenerative condition after Alzheimer’s disease, and the main cause of Parkinsonian syndrome.
Imagerie cérébrale Oumesmar Zujovic
Multiple Sclerosis (MS)
Multiple sclerosis (MS) is the second leading cause of acquired disability in young adults, after injury. It affects 120,000 people in France today, with 3,000 new cases diagnosed each year. This makes it a major public health issue, since it also...
Imagerie scientifique
Charcot’s disease or amyotrophic lateral sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS), or ‘Charcot’s disease’, is a progressive and fatal neuromuscular condition involving the gradual death of motor neurons, the neurons that control walking, speech, swallowing and breathing. This loss of motor...
marquage multiplex de lymphocytes dans un échantillon de tumeur cerebrale
Brain tumours
A tumour is formed of cells that multiply in an uncontrolled way, taking over the surrounding cells and, to varying degrees, disrupting brain function. A brain tumour can develop in any area of the brain.
Imagerie médicale Baulac
Epilepsy
The word ‘epilepsy’ originates from a Greek word meaning ‘to seize’, reflecting the sudden and unpredictable onset of seizures. In France, 600,000 people are affected by this chronic neurological disease, which can present with different symptoms...
Accident vasculaire cérébrale
Stroke (cerebrovascular accident, CVA)
A cerebrovascular accident, or stroke, is a sudden onset condition that causes motor deficits (movement of the limbs), loss of sensation and/or language problems.
Visages stylisés
Autism spectrum disorders
Autism, or autism spectrum disorder, is a neurodevelopmental disorder that has two main symptoms: persistent problems with communication and social interaction in a variety of contexts; and restricted and repetitive behaviour, interests and...
Visages bleus
Depression
Mental health, an essential component of our overall health, is a state of well-being, and an ability of the mind to function normally and respond appropriately to environmental stimuli. Mental disorders occur when this state of well-being is...
Imagerie cérébrale Gilles de la Tourette
Tourette's syndrome (TS)
Tourette’s syndrome (TS) was first identified in the 19th century by French neurologist Georges Gilles de la Tourette. It is a neuropsychiatric disorder with a genetic component characterised by sudden, brief and intermittent movements (motor tics)...
2 visages
Bipolar disorder
Although the word ‘bipolar’ is being increasingly used in the media, and sometimes misused, the disorder is in fact a serious and debilitating condition affecting around 3% of the population.

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