Guest researcher : Adrian ISAACS, "c9orf72 gene in FTD and ALS"

Published on: 30/05/2016 Reading time: 1 min

Professor Adrian Isaacs, neuroscientist at the London University College (UCL), was the Institut du Cerveau - ICM's guest on April 18, 2016. On this occasion, he discusses his research on C9orf72 gene, which unusual mutation is at the origin of two related diseases : frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

All our latest «Invited Researcher» videos’ on YouTube.

Our news on the subject

À la recherche de marqueurs d’imagerie dans la démence frontotemporale

Searching for Imaging Markers in Frontotemporal Dementia

Could exploring the relationships between different brain networks help us understand frontotemporal dementia (FTD)? This neurodegenerative disease, which progresses at varying rates, is often diagnosed late—when clinical signs are already severe. At...

01.07.2025 Research, science & health

Monocyte – un globule blanc qui se différencie en macrophage. Crédit : Université d’Edinbourg.

Discovery of a Macrophage Anomaly in Multiple Sclerosis

Certain patients with multiple sclerosis (MS) can partially regenerate myelin—the protective sheath that surrounds nerve fibers—which is damaged during the evolution of the disease. In studying how immune cells influence this remyelination...

12.19.2024 Research, science & health

Looking back at the “Brain to Market” Summer School 2024 dedicated to motor neurone disease

From September 9 to 13, the Open Brain School, the education center at Paris Brain Institute, organized the 10th edition of its flagship training program in neuroscience and entrepreneurship—dedicated to fostering innovation. This event brought the...

10.07.2024 Teaching & training

Interneurones. Crédit : UCLA Broad Stem Cell Research Center.

Stimulating specific neurons in the striatum stops compulsive behaviour

What if we could resist compulsions? These irrational behaviours, particularly common in obsessive-compulsive disorder (OCD), are hard to suppress. At Paris Brain Institute, Éric Burguière's team shows that we can anticipate them and block them...

09.10.2024 Research, science & health

Les nerfs moteurs présents dans la moelle épinière se projettent vers la périphérie, où ils entrent en contact avec les muscles, formant des connexions appelées jonctions neuromusculaires. Crédit : James N. Sleigh.

Ultrasound show unexpected effects on motor neuron disease

Over the past fifteen years, neurosurgeons have been perfecting a fascinating technique: using ultrasound to temporarily open the blood-brain barrier to facilitate the action of therapeutic molecules in the central nervous system. At Paris Brain...

09.05.2024 Research, science & health

Rett syndrome: a new gene therapy on the way

Gene therapy could be our best chance of treating Rett syndrome, a neurological disorder that causes severe intellectual and motor impairments. At Paris Brain Institute, Françoise Piguet and her colleagues have looked closely at brain cholesterol...

07.16.2024 Research, science & health

See all our news