Research, science & health

The anomalies underlying neurodegenerative diseases may arise during development—decades before the first symptoms appear. This hypothesis is gaining traction thanks to a new study published in Nature Communications. According to researchers from the...

Remembering past events in minute detail, revisiting them methodically, and reliving past emotions—this is the peculiarity of people with an exceptional memory of their own lives, known as autobiographical hypermnesia, or hyperthymesia. This...

In an article published in Nature Communications, researchers from 37 scientific institutions—including Paris Brain Institute—unveil the DREAM database: an ambitious project designed to centralize, share, and standardize data from research on sleep...

First described 60 years ago, chronic myoclonus following cerebral anoxia is now known as Lance-Adams syndrome. This is a severe disorder whose mechanisms were, until now, poorly understood. Geoffroy Vellieux, Vincent Navarro, and their colleagues at...

Thanks to 7T fMRI, researchers from Paris Brain Institute and NeuroSpin, the CEA's neuroimaging centre, are exploring the neural substrate of visual imagery at very high resolution for the first time. Their results, publiés [i] in Cortex, pave the...

Although every person’s personality is the result of genetic and environmental factors, these are not the only factors at play. Bassem Hassan and his team at Paris Brain Institute have discovered that, in fruit flies (drosophila), individuality also...

A study by Stéphanie Baulac’s team has revealed somatic mutations in different cell types in patients with type 2 focal cortical dysplasia. This disease causes drug-resistant epileptic seizures, for which the main treatment option is currently...

The ICEBERG cohort, initiated 10 years ago, is interested in studying factors predictive of the onset and progression of Parkinson’s disease.

Huntington's disease, a rare hereditary neurological disorder, is associated with an energy deficit that precedes the onset of symptoms and is closely linked to their progression. At Paris Brain Institute, Fanny Mochel and her colleagues are testing...

Could exploring the relationships between different brain networks help us understand frontotemporal dementia (FTD)? This neurodegenerative disease, which progresses at varying rates, is often diagnosed late—when clinical signs are already severe. At...

Certain patients with multiple sclerosis (MS) can partially regenerate myelin—the protective sheath that surrounds nerve fibers—which is damaged during the evolution of the disease. In studying how immune cells influence this remyelination...

What if we could resist compulsions? These irrational behaviours, particularly common in obsessive-compulsive disorder (OCD), are hard to suppress. At Paris Brain Institute, Éric Burguière's team shows that we can anticipate them and block them...