Skip to main content

Or 34,00 After 66% tax deduction

I make a monthly donation I make an IFI donation
Research, science & health

International recognition for Benedetta Bodini and Bruno Stankoff, for their work on multiple sclerosis

Published on: 29/12/2016 Reading time: 1 min
Benedetta Bodini et Bruno Stankoff

The publication of Benedetta Bodini and Bruno Stankoff, researchers at Paris Brain Institute, on the use of a new imaging technique in multiple sclerosis, was selected by Lancet Neurology among the top 5 of 2016 to improve the understanding and knowledge of this disease.

The article "Dynamic Imaging of Individual Remyelination Profiles in Multiple Sclerosis" was just recognized by Lancet Neurology as one of the top 5 publications of the year 2016 that have "improved understanding, or raised awareness on multiple sclerosis ". The journal Lancet Neurology is one of the leading journals in the field of neuroscience.

Paris Brain Institute researchers have developed a new imaging method to visualize neurons demyelination and remyelination, and quantify their degeneration.

The Lancet Neurology stated that "The use of pathology-specific imaging biomarkers is an innovative strategy to improve the understanding of underlying mechanisms in multiple sclerosis. Although MRI is particularly useful for diagnosis and clinical trials, PET (Positron Emission Tomography) extends the field of observation, as it was magnificently shown by a study of Bodini et al. on demyelination and remyelination. This study, carried out on 20 patients, has helped to develop a remyelination index that reflects the individual repair potential and that is inversely associated with the progression of the disability. ".

 

"I am very flattered that this publication was selected as one of the top five of the year by The Lancet Neurology; this strengthens and encourages us in our research. Using this technique, we will eventually be able to stratify patients according to their potential for spontaneous remyelination in order to adapt the treatment for the best. It is also useful to evaluate remyelinating drugs in clinical trials."– B. Bodini.

Sources

Dynamic imaging of individual remyelination profiles in multiple sclerosis.
https://www.ncbi.nlm.nih.gov/pubmed/26891452
Bodini B, Veronese M, García-Lorenzo D, Battaglini M, Poirion E, Chardain A, Freeman L, Louapre C, Tchikviladze M, Papeix C, Dollé F, Zalc B, Lubetzki C, Bottlaender M, Turkheimer F, Stankoff B. Ann Neurol. 2016 Feb 18.

Our news on the subject

Le développement du cerveau a une part d’aléatoire
The stochastic aspect of brain development
Although every person’s personality is the result of genetic and environmental factors, these are not the only factors at play. Bassem Hassan and his team at Paris Brain Institute have discovered that, in fruit flies (drosophila), individuality also...
05.12.2025 Research, science & health
Analyse MERSCOPE
New treatment pathways for brain malformation-linked focal epilepsy?
A study by Stéphanie Baulac’s team has revealed somatic mutations in different cell types in patients with type 2 focal cortical dysplasia. This disease causes drug-resistant epileptic seizures, for which the main treatment option is currently...
05.12.2025 Research, science & health
Un iceberg
The ICEBERG cohort, 10 years of collective scientific and medical mobilization
The ICEBERG cohort, initiated 10 years ago, is interested in studying factors predictive of the onset and progression of Parkinson’s disease.
05.15.2025 Research, science & health
La huntingtine est une protéine indispensable au développement embryonnaire, à la formation et au maintien du tissu cérébral.
Huntington's Disease: The Energy Hypothesis Gets Traction
Huntington's disease, a rare hereditary neurological disorder, is associated with an energy deficit that precedes the onset of symptoms and is closely linked to their progression. At Paris Brain Institute, Fanny Mochel and her colleagues are testing...
02.11.2025 Research, science & health
À la recherche de marqueurs d’imagerie dans la démence frontotemporale
Searching for Imaging Markers in Frontotemporal Dementia
Could exploring the relationships between different brain networks help us understand frontotemporal dementia (FTD)? This neurodegenerative disease, which progresses at varying rates, is often diagnosed late—when clinical signs are already severe. At...
01.07.2025 Research, science & health
Monocyte – un globule blanc qui se différencie en macrophage. Crédit : Université d’Edinbourg.
Discovery of a Macrophage Anomaly in Multiple Sclerosis
Certain patients with multiple sclerosis (MS) can partially regenerate myelin—the protective sheath that surrounds nerve fibers—which is damaged during the evolution of the disease. In studying how immune cells influence this remyelination...
12.19.2024 Research, science & health
See all our news