Research, science & health

Basic research in the field of nutrition has enabled to develop, in animals, a system regulating the expression of a gene through a specific diet leading to original therapeutic applications. Developed by a team from the Human Nutrition Unit (Inra...

Trisomy 21 is the first genetic cause of intellectual disabilities, and currently cognitive rehabilitation is the only therapeutic approach offered to patients. A phase II clinical trial conducted by an international team involving researchers from...

Professor Adrian Isaacs, neuroscientist at the London University College (UCL), was the Institut du Cerveau - ICM's guest on April 18, 2016. On this occasion, he discusses his research on C9orf72 gene, which unusual mutation is at the origin of two...

A specialist in genetics of epilepsy, Stephanie Baulac, co-responsible of the team "genetics and physiopathology of family epilepsies" at the Institut du Cerveau - ICM, is the winner of an ERC Consolidator Grant.

A major international conceptual diagnostic criteria and conceptual breakthrough program has been successfully launched and published, led by the UPMC and Institut du Cerveau - ICM researchers Professor Bruno Dubois and Professor Harald Hampel (AXA –...

A team coordinated by professor Emmanuel Flamand-Roze of the Pitié-Salpêtrière hospital, AP-HP, and researcher at the Brain and Spine Institute, has tested at the Institut du Cerveau - ICM Clinical Investigation Center, the efficiency of zonisamide...

In the context of World Parkinson's disease day on April 11th, the Institut du Cerveau - ICM focuses on the latest discoveries.

Hereditary spastic paraplegias are a heterogeneous group of pathologies and share clinical similarities with other neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).

In a rare and early form of Alzheimer's disease, Institut du Cerveau - ICM researchers have shown that, surprisingly, connectivity between neurons increases during the initial phase of the disease. This transitional increase would correspond to a...

For the first time in humans, an imaging study shows an early and protective role of the immune cells of the brain, called " microglial " cells, in Alzheimer's disease. Teams from the Sainte-Anne Hospital Center, from the CEA, from the Saint-Antoine...

For the first time, an animal model, deficient for DEPDC5 gene, responsible for familial focal epilepsy with cortical malformations, has been generated by Stéphanie Baulac and Eric Leguern's team.

For the first time, Claire Wyart's team has shown in the zebra fish, the existence of a sensory system within the spinal cord, capable of detecting and modulating movement. Identification of other parameters that can activate this system, and thus...