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A high tumour mutational burden (hypermutation) is observed in some gliomas 1, 2, 3, 4, 5; however, the mechanisms by which hypermutation develops and whether it predicts the response to immunotherapy are poorly understood.

Estimating the value of alternative options is a key process in decision-making. Human functional magnetic resonance imaging and monkey electrophysiology studies have identified brain regions, such as the ventromedial prefrontal cortex (vmPFC) and...

Where does our individuality come from? What makes us unique in our behavior? Could it all be in our brain? Prof. Bassem Hassan* and his team discovered a stochastic wiring mechanism of circuits in the fly’s brain at the origin of individual behavior...

To develop and launch a kit dedicated to sample preparation for single-cell RNA-sequencing

Cyril Atkinson-Clément (Institut du Cerveau - ICM) and Yulia Worbe (Sorbonne Université/APHP) in the team “normal and abnormal motor control: movement disorders and experimental therapeutics” at paris brain institute, show that the control of motor...

Paris, February 13, 2020 – The team of Nicolas Renier at Paris Paris Brain Institute has succeeded in reconstructing the entire cerebral vascular system of mice with unprecedented precision. This work has been conducted in collaboration with...

This year, 6 young Institut du Cerveau - ICM researchers were awarded a Marie Sklodowska-Curie Actions postdoctoral fellowship. A record!

Paris, February 5th 2020 - Bassem Hassan, head of the "Brain Development" team and Scientific Director of the Brain and Spinal Cord Institute (Institut du Cerveau - ICM), received the Roger de Spoelberch Prize for his research project in the field of...

On the occasion of the Institut du Cerveau 10th anniversary, FOCUS on the Charcot Library !!!

Because the quality of scientific discoveries depends very strongly on the match between research projects and the evolution of technology, Paris Brain Institute offers you, in this new series of articles, to discover the work carried out by its core...

The team led by Prof. Stéphane CHARPIER (Sorbonne Université) at the Brain and Spine Institute is describing live for the first time the neuronal changes during reoxygenation of the brain in anoxia in an experimental in vivo model.

Jaime de Juan-Sanz holds The Diane Barrière Chair « Molecular physiology of synaptic bioenergetics ». We met him in is new lab to talk about his background and research projects.