News

Is paying attention to the things around us necessary to perceive them? This seemingly simple question is far from having a consensual answer. To decide between the various existing hypotheses, Jianghao Liu and his colleagues at Paris Brain Institute...

The more we like our ideas, the faster we give them shape. But to be creative, you have to have a penchant for ideas that are out of the ordinary… This is what Alizée Lopez-Persem and Emmanuelle Volle, Inserm researchers at Paris Brain Institute...

Assessing a number of elements, whether individuals in a group, twigs in a nest, or fruit on a branch, is an essential skill in many animals. But the neural circuits on which it is based are still poorly understood. To remedy this lack of knowledge...

To adapt to the small and large events that give the world its ever-changing character, we use an essential ability: cognitive flexibility. It enables us to improvise in the event of disruptions on our morning commute, to cope with the unexpected...

Spinocerebellar ataxias are a very heterogeneous group of inherited diseases associated with degeneration of the cerebellum – a region at the back of the skull that plays an essential role in motor control. Patients have gait and balance disorders...

What if Alzheimer’s disease left its mark on the embryo? Khadijeh Shabani and her colleagues from the “Brain Development” team led by Bassem Hassan (Inserm) at Paris Brain Institute show that the amyloid precursor protein (APP) has a specific...

Thanks to the collaboration between teams from the AP-HP, the MedTech METAFORA biosystems, the Institute of Molecular Genetics of Montpellier, Cerba Healthcare, and more than 30 investigating centers coordinated by Prof. Fanny Mochel at Paris Brain...

Does humor appreciation have a brain signature? In a new study published in Neuropsychologia, Vadim Axelrod at Bar-Ilan University in Tel Aviv, in collaboration with Lionel Naccache (Sorbonne University, AP-HP) at Paris Brain Institute, decrypts the...

Unlike classic epileptic seizures that last only a few seconds or minutes, " status epilepticus" refers to a state of neuronal hyperactivity in the cerebral cortex that persists for several hours or days. When this condition occurs without a readily...

No treatment currently exists that can stop the silent progression of multiple sclerosis, and many promising drugs have proved ineffective in clinical trials. To reduce this failure rate and better predict the potential of candidate molecules...

Glioblastomas are the most common malignant tumors of the adult brain. They resist conventional treatment, including surgery, followed by radiation therapy and chemotherapy. Despite thisarmamentarium, glioblastomas inexorably recur. In a new study...

Léonie KOBAN and Hilke PLASMANN, researchers in the team "CIA: cognitive control - interoception - attention", have identified a novel brain marker using functional imaging that predicts our preference for immediate rewards over larger later rewards...