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Welcome to the “news” section of our website, where you'll find all the latest publications on our advances in research (Alzheimer's, Parkinson's, Charcot's disease, etc.), our upcoming events, etc.

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Ketamine and depression: a mechanism of the antidepressant effect reveal
Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant. Ketamine, usually used as an anesthetic, was administered...
10.06.2022 Research, science & health
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Genetics of early-onset parkinsonism with intellectual disability
A research team from the Paris Brain Institute (Inserm/CNRS/Sorbonne University/AP-HP) just identified mutations in familial cases with early-onset Parkinsonism and intellectual disability. Genetic studies on two affected siblings pairs highlighted...
09.29.2022 Research, science & health
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An open-source algorithm to help Alzheimer's disease diagnosis
The diagnosis of atypical forms of Alzheimer's disease is still sometimes difficult. Researchers from Paris Brain Institute have developed an automated algorithm to correlate the specificities of brain lesions with the symptoms associated with these...
09.18.2022 Research, science & health
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Computational model of brain complexity and function, a new research perspective
In a recent paper, published in Reviews of Modern Physics, Charley Presigny and Fabrizio de Vico Fallani (Inria) from the ARAMIS team from the Paris Brain Institute present a new mathematical model to decipher the brain organization and function in...
08.08.2022 Research, science & health
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Alzheimer's disease, a complex genetic susceptibility
Although Alzheimer's disease is not inherited in 95% of cases, nearly 75 genetic susceptibility factors - that is, factors that increase the risk to develop the disease - or protective factors - that decrease the probability to be affected - have...
07.11.2022 Research, science & health
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Status Epilepticus: new biomarkers to improve the prognosis of patients admitted to the ICU
A major neurological emergency, status epilepticus is defined as a persistent epileptic seizure. Exposing patients to irreversible brain lesions that cause serious cognitive sequelae, it requires intensive care, which may lead to sedation (artificial...
07.06.2022 Research, science & health
réseau lymphatique
3D mapping of the meningeal lymphatic network reveals new mysteries
Jean-Léon Thomas' group (Inserm, Paris Brain institute) just published a 3D mapping of the meningeal lymphatic network and the associated cerebrospinal fluid (CSF) drainage, both in mice and in humans. Beyond the identification of highly conserved...
07.05.2022 Research, science & health
Des personnages avec une ampoule qui symbolise la créativité
How do we explore our knowledge to be creative?
Coming up with a creative idea requires us to draw on all our previous knowledge. But how does this happen in our mind and in our brain? Emmanuelle Volle's group (Inserm) at the Frontlab of the Paris Brain Institute, in collaboration with the...
06.29.2022 Research, science & health
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Decision-making: a new distribution of tasks in our prefrontal cortex?
The team "Motivation, Brain and Behavior", co-directed by Mathias Pessiglione (Inserm) at the Paris Brain Institute, proposes in a study published in the Journal of Neuroscience a new approach to understand how our prefrontal cortex makes decisions.
06.23.2022 Research, science & health
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A better characterization of disinhibition in frontotemporal degeneration
Thanks to an approach combining behavioral assessment and brain imaging, a study conducted by the Paris Brain Institute's FrontLAB has led to a better characterization of a major symptom of frontotemporal degeneration, disinhibition. These results...
06.20.2022 Research, science & health
schéma
Visual mental imagery: a patient case suggests a new key brain network
Every day, we call upon a unique capacity of our brain, visual mental imagery, which allows us to visualise images, objects or people 'in our heads'. Based on the recent case of a patient with a specific brain lesion, Paolo Bartolomeo's group (Inserm...
06.09.2022 Research, science & health
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A new statistical method for improved brain mapping
Brain mapping consists in finding the brain regions associated with different traits, such as diseases, cognitive functions, or behaviours, and is a major field of research in neuroscience. This approach is based on statistical models and is subject...
05.23.2022 Research, science & health