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Metachromatic leukodystrophy is a rare genetic disorder that mainly affects young children and results in severe neurological symptoms accompanied by a loss of motor and intellectual capacities. At Paris Brain Institute, Françoise Piguet and her...

Multiple sclerosis is a heterogeneous disease whose manifestations vary considerably from patient to patient and whose course appears, on the surface, unpredictable. Hence, it is crucial to identify the factors that drive disability progression. In a...

A giant billboard flashes on the side of a country road. Why does it catch our attention more easily than other details in the landscape? At Paris Brain Institute, Tal Seidel Malkinson, Jacobo Sitt, Paolo Bartolomeo, and their colleagues show that...

Sometimes, in healthy tissues, mutated cells are seen that may or may not become malignant tumours. This phenomenon has already been described in the endometrium, oesophagus and epidermis. At Paris Brain Institute, Matthieu Peyre and his colleagues...

From the very first weeks of life, countless connections are forged between neurons to ensure the propagation of nerve signals. These connections gradually shape the final architecture of the brain, known as the connectome. Our ability to perform...

Nikolas Karalis joined the Brain Institute in January 2024. His work will focus on the fundamental link between brain activity and neurotransmitter balance.

Dafni Hadjieconomou joined Paris Brain Institute in September 2023. Her research will focus on the “brain-gut” axis, with the aim of identifying the fundamental, evolutionarily conserved mechanisms by which intestinal neurons regulate metabolism.

The C-BRAINS international PhD program invites applications for 13 PhD contracts, including 5 provided by Paris Brain Institute.

When brain oxygenation is cut off for a prolonged period, the electrical activity of the cerebral cortex is quickly reduced to zero. But that’s not the end of the story… Researchers at Paris Brain Institute, coordinated by Séverine Mahon, have shown...

What if the biological mechanisms that cause multiple sclerosis were triggered years before clinical diagnosis? This is what a team at Paris Brain Institute suggests in a new study published in Neurology. The researchers show that, on a population...

An Intellectual Development Disorder (IDD) is a cognitive skills development disorder beginning in early childhood. Despite advances in genetics, in around 50% of cases the cause of this neurodevelopmental disorder is still not identified. The ENCode...

On Thursday October 5, Camille Lakhlifi, a Université Paris Cité's PhD student at Paris Brain Institute (CNRS/Inserm/Sorbonne Université) won 1st prize from the jury at the international final of "Ma thèse en 180 secondes", the popular science...